Eczacılık Fakültesi: Recent submissions
Now showing items 1-20 of 46
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Preliminary investigations on acyl hydrazones bearing sulfonamides as inhibitors of the human Carbonic Anhydrase isoforms I, II, IX, and XII
(Bentham Science, 2025)Aim: The present study aims to identify the synthesis and structural characterization of acyl hydrazone- sulfonamide-containing compounds that were tested in vitro on human carbonic anhydrase (hCA) isoforms I, II, IX, and ... -
Antimicrobial resistance and inducible beta-lactamase synthesis in Pseudomonas aeruginosa strains isolated from nosocomial infections of various localizations
(Marmara University, 2025)Pseudomonas aeruginosa (P. aeruginosa) is a major opportunistic pathogen associated with nosocomial infections. The intrinsic resistance of P. aeruginosa to many antibiotics and the ability of P. aeruginosa to rapidly ... -
Synthesis of novel thiazole/thiadiazole conjugates of fluoroquinolones as potent antibacterial and antimycobacterial agents
(John Wiley and Sons Inc, 2025)Twenty azole-fluoroquinolone hybrids were designed and synthesized by conjugating thiazole and thiadiazole structures to ciprofloxacin and norfloxacin via a 2-oxoethyl bridge. The structures and purities of the synthesized ... -
Multikinase inhibition-mediated proliferative vitreoretinopathy therapy by nanoparticles in rabbits
(Molecular Vision, 2025)Purpose: To investigate the efficacy of nanoparticles in treating proliferative vitreoretinopathy (PVR) through clinical observation, histology, and immunohistochemistry, despite unsatisfactory surgical outcomes and failed ... -
Toplum eczacılarının hizmet içi eğitime yaklaşımlarının etik analizi: Gelecekte eczacılık hizmet içi eğitiminin nasıl olmasını hayal ediyoruz
(İstanbul Kent Üniversitesi, 2024)Toplum eczaneleri, ilaç ihtiyacını karşılayan sağlık birimleri olmanın ötesinde, sağlıkla ilgili endişeleri olanlar, bilgi ve güvenilir tavsiyeye ihtiyaç duyanlar için sağlık sistemiyle ilk temas noktasıdır. Bu ... -
Polymeric drug delivery systems: Production, characterization, and their in vitro and in vivo biological activities
(ICEMES, 2025)Polymeric drug delivery systems are produced using a variety of natural and synthetic polymers. Nano- and micro-scale drug delivery systems have been developed by employing synthetic polymers such as polylactic acid ... -
Development of sublingual nanofibrous mats for enhanced nutrient delivery: A novel approach using chitosan-based nanoparticles
(ICEMES, 2025)There are many different types of dietary supplements that provide vital chemicals to the people they need to stay healthy. Oral administration offers convenience, yet it also presents notable drawbacks, including the ... -
Characterization and anti-Alzheimer's effect of donepezil-loaded chitosan/polyethylene glycol nanospheres
(Editions de Sante, 2025)Among numerous dysfunctions associated with Alzheimer’s disease, cholinergic deficiency has been postulated as evidently influential. Despite donepezil’s ability to decelerate disease progression, drug’s pharmacokinetic ... -
A novel liposomal in-situ hydrogel formulation of hypericum perforatum L.: In vitro characterization and in vivo wound healing studies
(MDPI, 2025)Hypericum perforatum L. (H.P.) is a species with a well-documented history of use in wound healing practices across the globe. The objective of this study was twofold: firstly, to evaluate the in vivo efficacy of liposomal ... -
The methanolic extracts of Teucrium polium L. and Micromeria fruticosa (L.) Druce subsp. brachycalyx P. H. Davis improve diabetes in streptozotocin/nicotinamide-induced type 2 diabetic female Sprague Dawley rats
(Elsevier, 2023)Background: Teucrium polium and Micromeria fruticosa subspecies are known to be used in tradi tional medicine for diabetes treatment. Objective: The present study aimed to examine the potential antidiabetic effects and ... -
Vitamin B12-loaded chitosan-based nanoparticle-embedded polymeric nanofibers for sublingual and transdermal applications: Two alternative application routes for vitamin B12
(Elsevier, 2024)Alzheimer’s disease (AD) is a neurodegeneration type that is biologically recognizable via β-amyloid plaques and tau neurofibril tangles. Global estimation for the total count of individuals enduring AD will rise up to ... -
Design and in vitro evaluation of curcumin-loaded PLGA nanoparticle-embedded sodium alginate/gelatin 3D printed scaffolds for Alzheimer’s disease
(Elsevier, 2024)Background: Targeted nanoparticles (NPs) are aimed at improving clinical outcomes by enhancing the diagnostic and therapeutic efficacy of drugs in the treatment of Alzheimer’s disease (AD). Methods: Curcumin (CUR)-loaded ... -
A comparison of electrospinning and pressurized gyration: Production of empagliflozin-loaded polylactic acid/ polycaprolactone fibrous patches
(Royal Soc, 2025)Novel therapeutic strategies are essential for enhancing efficacy and accelerating the treatment of diabetes mellitus. This investigation focused on incorporating empagliflozin into a composite of polylactic acid ... -
Discovery of dual-inhibitor acyl hydrazones for acetylcholinesterase and carbonic anhydrase I/II: A mechanistic insight into Alzheimer's disease
(John Wiley and Sons Inc, 2025)This study presents the synthesis of various non-sulfonamide acyl hydrazone derivatives intended as multi-target ligands for the treatment of Alzheimer's disease. The derivatives were thoroughly characterized using advanced ... -
Development and characterization of liposomal systems for improved resveratrol delivery
(Kızılay Culture and Art, 2025)After the COVID-19 pandemic, consumer awareness of health and wellness has increased global interest in dietary supplements. The global food sup plement market has grown rapidly and is expected to continue. Resveratrol ... -
Production and characterization of propolis-loaded liposomes with a new formulation that can be used in mineral water
(Kızılay Culture and Art, 2025)The use of food supplements has increased significantly all over the world in the last decade. Propolis, which is frequently preferred as one of the food supplement ingredients, plays a role in antioxidant and ... -
Mitochondria-targeted spathulenol-loaded retinosomes for age-related macular degeneration
(Kızılay Culture and Art, 2025)Age-related macular degeneration (AMD) is a leading cause of vision loss, with mitochondrial dysfunction playing a key role in its progression. This study explores the use of spathulenol, a natural sesquiterpene with ... -
Liposomal coenzyme Q10/vitamin C: An innovative approach to enhance bioavailability andanti-inflammatory effects in neurological diseases via in vitro cell culture and in vivo animal tests
(Kızılay Culture and Art, 2025)Internal or external stressors may trigger a systemic hyperactive immune re sponse that results in widespread dysregulation and the potential for irrevers ible damage to vital organs. The potential of antioxidants such as ... -
Investigation of the antimicrobial activity of some plant extracts
(Kızılay Culture and Art, 2025)The use of antimicrobial plants in mineral water prevents the growth of pathogenic microorganisms, extends the shelf life of the product, and pro vides a natural alternative to chemical preservatives (1). Furthermore, ... -
In vitro investigation of antimicrobial activities of Camellia sinensis, Salvia officinalis, Aloe vera and Thymus vulgaris
(Kızılay Culture and Art, 2025)Acne vulgaris is a skin condition that affects people of various age groups worldwide. It can lead to psychological disorders by negatively impacting individuals’ social lives, self-confidence, physical appearance, and ...
