İstanbul Kent Üniversitesi Research and Academic Performance System
DSpace@Kent is an integrated information system that unifies the monitoring, analysis and reporting of scientific research and academic performance at İstanbul Kent University.
Recent Submissions
Item type:Item, Türk Mahkemelerinin bilimsel görüşlerden yararlanması hakkında bazı değerlendirmeler(Çukurova Üniversitesi, 2026) Pehlivanoğlu, Murat Can; Özcan, Mustafa Emin4721 sayılı Türk Medeni Kanunu m. 1(3) uyarınca “hâkim, karar verirken bilimsel görüşlerden ve yargı kararlarından yararlanır”. Bununla beraber, uygulamada hâkimin bilimsel görüşlerden ve dolayısıyla öğretiden hangi ölçüde yararlandığı bilinmemektedir. Oysa mahkemelerin bilimsel görüşlerden faydalanma ölçüsünün tespiti birçok açıdan önem taşımaktadır. Bu anlayışla, eldeki çalışmada, mahkeme kararlarını tarayan bir veri tabanı yoluyla hazırlanan veri seti üzerinden bir kısım güncel mahkeme kararı incelenmiştir. Bu kararlarda atıf yapılan bilimsel görüşler tespit edilmiş, sınıflandırılmış ve değerlendirilmiştir. Çalışmanın sonucunda Türk hukuku uygulamasında bilimsel görüşler içerisinden en çok “yorumlayıcı” nitelikte olanlardan faydalanıldığı ve yine en çok kitap türünde somutlaşan bilimsel görüşlere ilgi gösterildiği tespit edilmiştir. Bununla beraber, atıflara yansıdığı ölçüde, Türk hukuku uygulamasında bilimsel görüşlerden yararlanma oranının düşük olduğu anlaşılmıştır.Item type:Item, Preventing Bakri balloon puncture during cesarean section in placenta previa: Fundal fixation Temur technique(Springer Nature, 2025) Temur, Muzaffer; Karaşin, Süleyman SerkanPlacenta previa is a major risk factor for obstetric hemorrhage. Bakri balloon tamponade (BBT) is a well established uterine-sparing method, but balloon puncture during uterine closure may compromise its effectiveness. We present a fundal fixation technique, a simple modification involving temporary fundal fixation of the balloon catheter to displace it away from the hysterotomy site during closure. This technical report outlines the method and summarizes the outcomes from four cases of placenta previa that were managed successfully. This fundal fixation technique is a safe and effective method for minimizing balloon puncture risk during cesarean sections.Item type:Item, Artificial intelligence meets medical rarity: Evaluating ChatGPT’s responses on post-orgasmic illness syndrome(Springer Nature, 2025) Sökmen, Doğukan; Albayrak, Ahmet Tevfik; Sertkaya, Zülfü; Başağa, Yaşar; Şerefoğlu, Ege CanPost-Orgasmic Illness Syndrome (POIS) is a rare and debilitating condition characterized by systemic and cognitive symptoms following ejaculation. As patients increasingly seek health information from artificial intelligence (AI) tools such as ChatGPT, evaluating the accuracy, consistency, and readability of these responses is especially important in the context of underrecognized conditions like POIS, where patients often encounter limited access to specialist care and evidence-based educational resources. This makes generative AI a likely source of health information, underscoring the need to evaluate the accuracy, consistency, and readability of its outputs. This study assessed the performance of ChatGPT version 4o (ChatGPT-4o) in generating patient-directed responses to POIS-related questions. Sixteen real-world questions were selected across four content domains: epidemiology, treatment, treatment risks, and counseling. Each question was submitted to ChatGPT-4o on two different days using separate accounts. Responses were independently graded by three English-speaking urologists with expertise in men’s sexual health and andrology using a validated 4-point scale: “correct and comprehensive,” “correct but inadequate,” “mixed correct and incorrect,” and “completely incorrect.” Reproducibility was defined by whether the two responses received the same grading category, and Cohen’s kappa coefficient (κ) was calculated to measure inter-rater agreement. Readability was assessed using the Gunning Fog Index (GFI). ChatGPT-4o demonstrated high performance in the epidemiology and counseling domains, achieving 100% accuracy and 100% reproducibility (κ = 1.00). However, accuracy dropped to 50% in the treatment and risk domains, with lower reproducibility (κ = 0.25). Readability scores worsened significantly from Day 1 to Day 2 across all domains (p < 0.05), indicating a shift toward more linguistically complex, less accessible language. While ChatGPT-4o shows potential in supporting patient education for rare conditions like POIS, its variability in treatment content and elevated language complexity limit its reliability as a stand-alone medical resource. These findings underscore the need for expert oversight and further model refinement before large language models can be safely integrated into clinical patient communication.Item type:Item, Determination of hydrocortisone and cortisone in artificial saliva by spray assisted fine droplet formation liquid phase microextraction coupled to LC-MS/MS(Springer Nature, 2026) Gürsoy, Selim; Bodur, Süleyman; Atakol, Arda; Bakırdere, SezginHydrocortisone and cortisone are clinically informative steroids whose joint measurement at low concentrations is essential for ratio-reliable interpretation. A spraying-assisted fine droplet formation liquid-phase microextraction (SA-FDF-LPME) was combined with liquid chromatography–tandem mass spectrometry (LC–MS/MS) for simultaneous quantitation in saliva-type matrices as part of a method-development study. Method parameters were optimized to secure chromatographic resolution, stable ion ratios, and high sensitivity. Under direct injection, LOD/LOQ values were 1.05/3.50 µg kg–1 for cortisone and 0.80/2.68 µg kg–1 for hydrocortisone, with dynamic ranges of 3.65–150.77 and 2.59–268.45 µg kg–1, respectively. With SA-FDF-LPME coupled to LC–MS/MS, LOD/LOQ were 0.0164/0.0547 µg kg–1 for cortisone and 0.0734/0.245 µg kg–1 for hydrocortisone, and dynamic ranges were 0.049–4.983 and 0.210–5.50 µg kg–1, respectively. Accuracy was established by pre-extraction spiking at different concentrations in two artificial saliva formulations. Using external-standard calibration, recoveries were 105.3–129.4%/110.4–141.1% for cortisone and 110.0–134.9%/94.1–142.8% for hydrocortisone; with matrix-matched calibration, recoveries were 80.3–103.2%/98.1–117.8% for cortisone and 79.8–105.7%/97.3–114.0% for hydrocortisone. The developed SA-FDF-LPME–LC–MS/MS method enables sensitive, accurate, and simultaneous quantification of hydrocortisone and cortisone at saliva-relevant concentrations and offers a practical platform for selective bioanalysis of related small molecules.Item type:Item, Laparoscopic excision of an accessory cavitated uterine malformation in an adolescent patient(Elsevier, 2026) Bıyık, İsmail; Cubo Abert, Montserrat; Hatırnaz, ŞafakObjective: To demonstrate the laparoscopic, uterus-sparing excision of an accessory cavitated uterine malformation (ACUM) in an adolescent patient and to emphasize the importance of accurate preoperative imaging for intraoperative localization. Setting: Tertiary referral center for minimally invasive gynecologic surgery. Participants: An 18-year-old adolescent patient presenting with severe dysmenorrhea and chronic pelvic pain refractory to medical treatment. Interventions: Laparoscopic excision of a noncommunicating accessory cavitated uterine lesion with preservation of the main uterine cavity. Conclusion: Preoperative transabdominal ultrasonography and magnetic resonance imaging demonstrated a 35 × 43 mm cystic lesion located in the left anterior uterine wall, clearly separated from the endometrial cavity and consistent with ACUM. During laparoscopy, no obvious uterine bulging was observed, making intraoperative localization challenging. A targeted myometrial incision allowed identification and complete excision of the lesion, which contained chocolate-colored fluid and was lined with endometrium-like tissue. The main uterine cavity was preserved, and layered myometrial reconstruction was performed. Histopathological examination confirmed the diagnosis of ACUM. Laparoscopic uterus-sparing excision is a safe and effective treatment option for adolescent patients with ACUM when guided by accurate preoperative imaging.
