Yazar "Ulusoy Güzeldemirci, Nuray" için listeleme
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Discovery of dual-inhibitor acyl hydrazones for acetylcholinesterase and carbonic anhydrase I/II: A mechanistic insight into Alzheimer's disease
Dinçel, Efe Doğukan; Kuran, Ebru Didem; Demir, Yeliz; Sucu, Bilgesu Onur; Gülçin, İlhami; Ulusoy Güzeldemirci, Nuray (John Wiley and Sons Inc, 2025)This study presents the synthesis of various non-sulfonamide acyl hydrazone derivatives intended as multi-target ligands for the treatment of Alzheimer's disease. The derivatives were thoroughly characterized using advanced ... -
Novel hydrazide-hydrazone containing 1,2,4-triazole as potent inhibitors of antiapoptotic protein Bcl-xL: Synthesis, biological evaluation, and docking studies
Kuran, Ebru Didem; Üner, Burcu; Çam, Muhammet Emin; Ulusoy Güzeldemirci, Nuray (John Wiley and Sons Inc, 2024)This study describes the synthesis and characterization of a series of novel hydrazide-hydrazone derivatives containing a 1,2,4-triazole ring. The compounds were characterized using various spectroscopic techniques, such ... -
Preliminary investigations on acyl hydrazones bearing sulfonamides as inhibitors of the human Carbonic Anhydrase isoforms I, II, IX, and XII
Dinçel, Efe Doğukan; Kuran, Ebru Didem; Ece, Abdulilah; Başoğlu Ünal, Faika; Renzi, Gioele; Badii, Gloria; Carta, Fabrizio; Supuran, Cladiu T.; Ulusoy Güzeldemirci, Nuray (Bentham Science, 2025)Aim: The present study aims to identify the synthesis and structural characterization of acyl hydrazone- sulfonamide-containing compounds that were tested in vitro on human carbonic anhydrase (hCA) isoforms I, II, IX, and ...
