Yazar "Yazır, Yusufhan" için listeleme
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Anti-Alzheimer's effect of memantine/donepezil/metformin-loaded PVA/PEO composite nanofibers produced by pressurized gyration: Production, characterization, and in vitro evaluation
Güler, Ece; Kopuz, Ayşen; Ertaş, Büşra; Yılmaz Göler, Ayşe Mine; Yazır, Yusufhan; Kalaskar, Deepak M.; Çam, Muhammet Emin (Editions de Sante, 2024)In this study, memantine (MM) and donepezil (DO) were combined with metformin (MF) as a new approach to Alzheimer’s disease (AD) treatment sublingually. MM, DO, and MF were loaded in polyvinyl alcohol (PVA)/ polyethylene ... -
Effects of different pulp-capping materials on cell death signaling pathways of lipoteichoic acid-stimulated human dental pulp stem cells
Kuru, Sinem; Sepet, Elif; İrez, Tülay; Aktaş, Esin; Yazır, Yusufhan; Duruksu, Gökhan; Osmanoğlu Akyol, Ebru; Ergüven, Mine (Springer, 2021)Abstract Purpose: This study aimed to evaluate the response of dental pulp stem cells (DPSCs) cultured with and without lipoteichoic acid (LTA) to different pulp-capping materials. Methods: The cells were cultured and ... -
Fabrication of oro-dispersible sodium valproate loaded nanofibrous patches for immediate epileptic innervation
Güler, Ece; Yekeler, Hümeyra Betül; Özdemir Kumral, Zarife N.; Parviz, Gita; Özcan, Gül S.; Üner, Burcu; Demirbaş, Sinem G.; Ayyıldız, Simge; Yazır, Yusufhan; Kalaskar, Deepak; Çam, Muhammet Emin (American Chemical Society, 2024)Epilepsy is one of the oldest neurological disorders discovered by mankind. This condition is firmly coupled with unprovoked seizures stimulated by irrepressible neuroelectrical blasts. Orally taken valproate family has ... -
In vitro neuroprotective effect evaluation of donepezil-loaded PLGA nanoparticles-embedded PVA/PEG nanofibers on SH-SY5Y cells and AP-APP plasmid related Alzheimer cell line model
Güler, Ece; Yekeler, Hümeyra Betül; Üner, Burcu; Doğan, Murat; Asghar, Asima; Ikram, Fakhera; Yazır, Yusufhan; Gündüz, Oğuzhan; Kalaskar, Deepak M.; Çam, Muhammet Emin (John Wiley and Sons Inc, 2024)Recently developed nanoparticles and nanofibers present new brain-specific treatment strategies, especially for Alzheimer's disease treatment. In this study, donepezil (DO)-loaded PLGA nanoparticles (DNP) are embedded in ... -
The methanolic extracts of Teucrium polium L. and Micromeria fruticosa (L.) Druce subsp. brachycalyx P. H. Davis improve diabetes in streptozotocin/nicotinamide-induced type 2 diabetic female Sprague Dawley rats
Sermet, Sinan; Çam, Muhammet Emin; Hazar Yavuz, Ayşe Nur; Taşkın, Turgut; Kabataş, Gül Sinemcan; Yazır, Yusufhan; Kabasakal, Levent; Elçioğlu, Hatice Kübra (Elsevier, 2023)Background: Teucrium polium and Micromeria fruticosa subspecies are known to be used in tradi tional medicine for diabetes treatment. Objective: The present study aimed to examine the potential antidiabetic effects and ... -
Sublingual administration of Teucrium polium-loaded nanofibers with ultra-fast release in the treatment of diabetes mellitus: In vitro and in vivo evaluation
Polat, Elif Beyzanur; Hazar Yavuz, Ayşe Nur; Güler, Ece; Özcan, Gül Sinemcan; Taşkın, Turgut; Duruksu, Gökhan; Elçioğlu, Hatice Kübra; Yazır, Yusufhan; Çam, Muhammet Emin (Elsevier, 2024)In this study, Teucrium polium (TP) methanolic extract, which has antidiabetic activity and protects the β-cells of the pancreas, was loaded in polyethylene oxide/sodium alginate nanofibers by electrospinning and administered ...
