Konu "Leigh disease" için listeleme
Toplam kayıt 2, listelenen: 1-2
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Assessing the performance of Coenzyme Q10 loaded DQAsomes to treat Leigh syndrome caused by NDUFS4 knockout
(Editions de Sante, 2024)Homozygous mutations in the NDUFS4 gene result in one of the many autosomal recessive forms of Leigh syndrome (LS), which impairs mitochondrial complex I function. In time, this disorder results in mental and motor ... -
DQAsomes as a coenzyme Q10 delivery vehicle: A step forward therapy in leigh disease
(Springer Nature, 2024)Leigh syndrome (LS), a severe neurometabolic disorder caused by mitochondrial dysfunction, is often linked to coenzyme Q10 (CoQ10) defciency. This study investigated using dequalinium chloride to create CoQ10-loaded ...
