Güncel Gönderiler: Eczacılık Fakültesi
Toplam kayıt 50, listelenen: 21-40
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Mitochondria-targeted spathulenol-loaded retinosomes for age-related macular degeneration
(Kızılay Culture and Art, 2025)Age-related macular degeneration (AMD) is a leading cause of vision loss, with mitochondrial dysfunction playing a key role in its progression. This study explores the use of spathulenol, a natural sesquiterpene with ... -
Liposomal coenzyme Q10/vitamin C: An innovative approach to enhance bioavailability andanti-inflammatory effects in neurological diseases via in vitro cell culture and in vivo animal tests
(Kızılay Culture and Art, 2025)Internal or external stressors may trigger a systemic hyperactive immune re sponse that results in widespread dysregulation and the potential for irrevers ible damage to vital organs. The potential of antioxidants such as ... -
Investigation of the antimicrobial activity of some plant extracts
(Kızılay Culture and Art, 2025)The use of antimicrobial plants in mineral water prevents the growth of pathogenic microorganisms, extends the shelf life of the product, and pro vides a natural alternative to chemical preservatives (1). Furthermore, ... -
In vitro investigation of antimicrobial activities of Camellia sinensis, Salvia officinalis, Aloe vera and Thymus vulgaris
(Kızılay Culture and Art, 2025)Acne vulgaris is a skin condition that affects people of various age groups worldwide. It can lead to psychological disorders by negatively impacting individuals’ social lives, self-confidence, physical appearance, and ... -
Antimicrobial effects of silver nanoparticles possibly used in food packaging
(Kızılay Culture and Art, 2025)Microbial contamination in food industry is a major issue resulting in wast ed products and poses a threat to public health through foodborne illnesses. Silver nanoparticles (AgNPs) have strong antimicrobial properties ... -
Acute toxicity assessment of powdered and liposomal resveratrol that can be used in mineral water
(Kızılay Culture and Art, 2025)Liposomes are now considered the most commonly used nanocarriers for various potentially active hydrophobic and hydrophilic molecules due to their high biocompatibility, biodegradability, and low immunogenicity. Li ... -
Assessment of the cytotoxic effects of the powder of Şalgam, a lactic acid fermented beverage based on black carrot, on breast carcinoma
(Kızılay Culture and Art, 2025)Recent advancements in phytotherapy have led to a surge in research fo cused on the therapeutic potential of plant extracts for the management and supportive care of various medical conditions. Emerging research has ... -
Targeted ‘Tfam’ activation and ‘Mitoq’ therapy for pearson syndrome
(Kızılay Culture and Art, 2025)This study investigates a novel therapeutic strategy for Pearson syndrome by combining Mitochondrial Transcription Factor A (TFAM) activation with the antioxidant MitoQ in a dual-loaded nanoparticle system. Pearson syndrome, ... -
Association of TOLLIP mRNA expression and TOLLIP rs5743899A/G, TOLLIP rs3750920C/T, and IL 10 1082G/A single nucleotide polymorphisms with susceptibility to tuberculosis
(Springer Nature, 2025)The early innate host immune response is crucial in the susceptibility to tuberculosis (TB). This study aimed to investigate the potential role of Toll-interacting protein (TOLLIP), a negative regulator of the human ... -
Antiviral properties of essential oil mixture: Modulation of E7 and E2 protein pathways in human papillomavirus (HPV) infection
(Elsevier, 2024)Ethnopharmacological relevance: Clove is used in Indian and Chinese traditional medicine for viral diseases. Palmarosa essential oils have been traditionally used in India and Southeast Asia since ancient times and ... -
Fabrication of oro-dispersible sodium valproate loaded nanofibrous patches for immediate epileptic innervation
(American Chemical Society, 2024)Epilepsy is one of the oldest neurological disorders discovered by mankind. This condition is firmly coupled with unprovoked seizures stimulated by irrepressible neuroelectrical blasts. Orally taken valproate family has ... -
The role of AMP-activated protein kinase activators on energy balance and cellular metabolism in type 2 diabetes mellitus
(Elsevier, 2024)Type 2 Diabetes Mellitus (T2DM) is a growing health concern that leads to increased morbidity and mortality rates worldwide. A protein complex called AMP-activated protein kinase (AMPK) regulates energy balance within ... -
DQAsomes as a coenzyme Q10 delivery vehicle: A step forward therapy in leigh disease
(Springer Nature, 2024)Leigh syndrome (LS), a severe neurometabolic disorder caused by mitochondrial dysfunction, is often linked to coenzyme Q10 (CoQ10) defciency. This study investigated using dequalinium chloride to create CoQ10-loaded ... -
Diyet türleri
(Ankara Nobel Tıp Kitabevleri, 2024)Sağlıklı bir diyet, aşırı alım olmaksızın enerjik ve fizyolojik ihtiyaçları desteklemek için makro besin öğelerinin uygun oranlarda tüketildiği, aynı zamanda vücudun fizyolojik ihtiyaçlarını karşılamak için yeterli mikro ... -
Sublingual β-Glucan/Vitamin C-loaded nanoparticle-embedded polyethylene oxide nanofibrous mats
(Editions de Sante, 2024)Nutritional supplements available in various forms provide the consumer with essential molecules demanded for well-being retention. Despite the conveniences provided by oral administration, significant disadvantages such ... -
In vitro neuroprotective effect evaluation of donepezil-loaded PLGA nanoparticles-embedded PVA/PEG nanofibers on SH-SY5Y cells and AP-APP plasmid related Alzheimer cell line model
(John Wiley and Sons Inc, 2024)Recently developed nanoparticles and nanofibers present new brain-specific treatment strategies, especially for Alzheimer's disease treatment. In this study, donepezil (DO)-loaded PLGA nanoparticles (DNP) are embedded in ... -
Evaluation of the mesalazine-loaded nanoparticles-embedded BSA hydrogels for the ulcerative colitis treatment
(ACG Publications, 2024)Ulcerative colitis (UC) is a chronic inflammatory bowel disease mainly affecting the colon and remains a challenging disease to manage clinically with its relapsing-remitting course. Traditional treatments for this ... -
Novel hydrazide-hydrazone containing 1,2,4-triazole as potent inhibitors of antiapoptotic protein Bcl-xL: Synthesis, biological evaluation, and docking studies
(John Wiley and Sons Inc, 2024)This study describes the synthesis and characterization of a series of novel hydrazide-hydrazone derivatives containing a 1,2,4-triazole ring. The compounds were characterized using various spectroscopic techniques, such ... -
Comparison of the effect of UVB application on the antioxidant properties of different mushroom species with vitamins D2 and D3
(Marmara University, 2024)This study aimed to determine the effect of UVB application on different mushrooms and their antioxidant properties and compare their properties with pure vitamins D2 and D3. In the study, as without UVB, with medium UVB ... -
Anti-Alzheimer's effect of memantine/donepezil/metformin-loaded PVA/PEO composite nanofibers produced by pressurized gyration: Production, characterization, and in vitro evaluation
(Editions de Sante, 2024)In this study, memantine (MM) and donepezil (DO) were combined with metformin (MF) as a new approach to Alzheimer’s disease (AD) treatment sublingually. MM, DO, and MF were loaded in polyvinyl alcohol (PVA)/ polyethylene ...
