Güncel Gönderiler: Istanbul Kent University Institutional Repository
Toplam kayıt 1062, listelenen: 341-360
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Fransa siyasetinde belirsizlikler dönemi: İkinci Macron iktidarı ve sonrasına dair bir analiz
(İstanbul Aydın Üniversitesi, 2024)2017 yılından beri Fransa siyasetine damgasını vuran genç ve liberal Cumhurbaşkanı Emmanuel Macron, 2017 ve 2022’de iki defa cumhurbaşkanlığı seçimlerini kazanmasına karşın, ilk dönemde sahip olduğu Ulusal Meclis ... -
U.S.–China competition: A power transition perspective
(World Scientific, 2024)U.S.–China competition has been widely viewed as the most important feature of world politics that will shape the emerging interna tional order. Whereas Washington increasingly sees Beijing as the sole great power with ... -
Determination of COL1A1 rs1800012 polymorphism related to ligament and tendon injury in Turkish professional bodybuilders: Experimental research
(Türkiye Klinikleri Yayınevi, 2024)Objective: Athletic performance is affected by genetic and environmental factors. Bodybuilding has been increasing around the world in recent years and it is accepted that the factors affecting athletic performance are the ... -
Evaluation of the mesalazine-loaded nanoparticles-embedded BSA hydrogels for the ulcerative colitis treatment
(ACG Publications, 2024)Ulcerative colitis (UC) is a chronic inflammatory bowel disease mainly affecting the colon and remains a challenging disease to manage clinically with its relapsing-remitting course. Traditional treatments for this ... -
Çubuk Barajı'nın açılışı ve sonrasındaki gelişmeler
(İstanbul Üniversitesi, 2024)Türkiye Cumhuriyeti’nin ilk barajı olan Çubuk Barajı ile Su Süzgeci ve Filtre İstasyonu, Başbakan İsmet İnönü’nün yanı sıra devlet erkânı ve yabancı diplomatların da katıldığı bir törenle 3 Kasım 1936’da açılmıştır. ... -
Çubuk Barajı'nın yapımına yol açan etkenler
(İstanbul Üniversitesi, 2024)Kuraklık ve sel gibi iklim değişikliklerinden oldukça etkilenen başkent Ankara açısından, düzenli bir su akışının sağlanması ekonomik ve sosyal açıdan büyük bir öneme sahiptir. Bu bağlamda şehrin su ihti yacının istikrarlı ... -
Novel hydrazide-hydrazone containing 1,2,4-triazole as potent inhibitors of antiapoptotic protein Bcl-xL: Synthesis, biological evaluation, and docking studies
(John Wiley and Sons Inc, 2024)This study describes the synthesis and characterization of a series of novel hydrazide-hydrazone derivatives containing a 1,2,4-triazole ring. The compounds were characterized using various spectroscopic techniques, such ... -
Comparison of the effect of UVB application on the antioxidant properties of different mushroom species with vitamins D2 and D3
(Marmara University, 2024)This study aimed to determine the effect of UVB application on different mushrooms and their antioxidant properties and compare their properties with pure vitamins D2 and D3. In the study, as without UVB, with medium UVB ... -
Anti-Alzheimer's effect of memantine/donepezil/metformin-loaded PVA/PEO composite nanofibers produced by pressurized gyration: Production, characterization, and in vitro evaluation
(Editions de Sante, 2024)In this study, memantine (MM) and donepezil (DO) were combined with metformin (MF) as a new approach to Alzheimer’s disease (AD) treatment sublingually. MM, DO, and MF were loaded in polyvinyl alcohol (PVA)/ polyethylene ... -
Development of thermosensitive liposome-containing in-situ gel systems for intranasal administration of thiocolchicoside and in vivo evaluation in a rabbit model
(Taylor and Francis Ltd., 2024)ABSTRACT Aim: Thiocolchicoside (THC) is a drug under the category of BCS III. Due to its high molecular weight, it has poor oral bioavailability and low skin permeability. This study aims to find an alternative delivery ... -
Direct colorimetric detection of triacetone triperoxide explosive by hydroxylamine-mediated Fenton chemistry catalyzed by goethite nanoparticles
(Elsevier, 2024)Due to the absence of nitro groups or aromatic structures in its structure, spectrophotometric methods that can directly determine triacetone triperoxide (TATP) are absent. In the proposed study, a molecular spectroscopic ... -
Prolonged release niosomes for ocular delivery of loteprednol: Ocular distribution assessment on dry eye disease induced rabbit model
(Springer, 2024)Loteprednol etabonate (LE) is a topical corticosteroid for the symptomatic management of ocular conditions, encompassing both allergic and infectious etiologies. Owing to the dynamic and static barriers of the eye, LE ... -
Donepezil/Curcumin-Loaded Nanoparticles-Embedded Microneedles for the treatment of Alzheimer’s disease: In vitro evaluation
(Avestia Publishing, 2024)Alzheimer’s disease (AD) is an insidious neurodegenerative disease that slowly deteriorates and seriously impairs the activity of daily living (ADL) of those who suffer from. Although the precise pathophysiology of AD ... -
A novel high-efficiency transdermal patches for combinational therapy of Alzheimer's disease: Donepezil/vitamin B12-loaded nanofibers
(Editions de Sante, 2023)Improving clinical practice in disease-modifying therapies is an important strategy in coping with the progressive course of Alzheimer’s Disease (AD). This study aimed to develop DO and VB12-loaded nanofibers (DO/VB12- ... -
Gilaburu (Viburnum opulus L.) fruit extract has potential therapeutic and prophylactic role in a rat model of acetic acid-induced oxidant colonic damage
(Elsevier, 2024)Ethnopharmacological relevance: Ulcerative colitis (UC) which has a global impact on the health care system with its recurrent and incompletely curable characteristics, affects the patients’ quality of life. Gilaburu (GB; ... -
Physical activity and nutrition therapy in childhood obesity
(IKSAD Publications, 2024)The aim of our study was to evaluate the effects of regular physical activity and healthy eating treatment in childhood obesity. Obesity is defined by the World Health Organization (WHO) as "abnormal or excessive fat ... -
Sublingual administration of Teucrium polium-loaded nanofibers with ultra-fast release in the treatment of diabetes mellitus: In vitro and in vivo evaluation
(Elsevier, 2024)In this study, Teucrium polium (TP) methanolic extract, which has antidiabetic activity and protects the β-cells of the pancreas, was loaded in polyethylene oxide/sodium alginate nanofibers by electrospinning and administered ... -
Enhancement of in-vivo cellular uptake of Coenzyme Q10 using saponin derivatives in rTALAP transgenic mice model
(Editions de Sante, 2024)Pancreatic cancer remains a significant contributor to cancer-related mortality, with pancreatic ductal adeno carcinoma (PDAC) being particularly challenging to treat. Coenzyme Q10 (CoQ10), a hydrophobic antioxidant crucial ... -
Assessing the performance of Coenzyme Q10 loaded DQAsomes to treat Leigh syndrome caused by NDUFS4 knockout
(Editions de Sante, 2024)Homozygous mutations in the NDUFS4 gene result in one of the many autosomal recessive forms of Leigh syndrome (LS), which impairs mitochondrial complex I function. In time, this disorder results in mental and motor ... -
Fizyoterapistlerde kas iskelet sistemi sorunlarının iş doyumu, uyku ve yaşam kalitesi üzerine etkisinin incelenmesi
(Türkiye Fizyoterapistler Derneği, 2023)Amaç: Bu çalışmanın amacı fizyoterapistlerde mevcut olan kas-iskelet sistemi sorunlarının iş doyumuna, uyku kalitesine ve yaşam kalitesine etkisini incelemektir. Yöntem: Araştırmamıza aktif çalışan 86 fizyoterapist ...
