Başlık için Eczacılık Meslek Bilimleri Bölümü listeleme
Toplam kayıt 29, listelenen: 1-20
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Anti-Alzheimer's effect of memantine/donepezil/metformin-loaded PVA/PEO composite nanofibers produced by pressurized gyration: Production, characterization, and in vitro evaluation
(Editions de Sante, 2024)In this study, memantine (MM) and donepezil (DO) were combined with metformin (MF) as a new approach to Alzheimer’s disease (AD) treatment sublingually. MM, DO, and MF were loaded in polyvinyl alcohol (PVA)/ polyethylene ... -
Antiviral properties of essential oil mixture: Modulation of E7 and E2 protein pathways in human papillomavirus (HPV) infection
(Elsevier, 2024)Ethnopharmacological relevance: Clove is used in Indian and Chinese traditional medicine for viral diseases. Palmarosa essential oils have been traditionally used in India and Southeast Asia since ancient times and ... -
Characterization and anti-Alzheimer's effect of donepezil-loaded chitosan/polyethylene glycol nanospheres
(Editions de Sante, 2025)Among numerous dysfunctions associated with Alzheimer’s disease, cholinergic deficiency has been postulated as evidently influential. Despite donepezil’s ability to decelerate disease progression, drug’s pharmacokinetic ... -
A comparison of electrospinning and pressurized gyration: Production of empagliflozin-loaded polylactic acid/ polycaprolactone fibrous patches
(Royal Soc, 2025)Novel therapeutic strategies are essential for enhancing efficacy and accelerating the treatment of diabetes mellitus. This investigation focused on incorporating empagliflozin into a composite of polylactic acid ... -
Comparison of the effect of UVB application on the antioxidant properties of different mushroom species with vitamins D2 and D3
(Marmara University, 2024)This study aimed to determine the effect of UVB application on different mushrooms and their antioxidant properties and compare their properties with pure vitamins D2 and D3. In the study, as without UVB, with medium UVB ... -
Design and in vitro evaluation of curcumin-loaded PLGA nanoparticle-embedded sodium alginate/gelatin 3D printed scaffolds for Alzheimer’s disease
(Elsevier, 2024)Background: Targeted nanoparticles (NPs) are aimed at improving clinical outcomes by enhancing the diagnostic and therapeutic efficacy of drugs in the treatment of Alzheimer’s disease (AD). Methods: Curcumin (CUR)-loaded ... -
Development and characterization of liposomal systems for improved resveratrol delivery
(Kızılay Culture and Art, 2025)After the COVID-19 pandemic, consumer awareness of health and wellness has increased global interest in dietary supplements. The global food sup plement market has grown rapidly and is expected to continue. Resveratrol ... -
Development of sublingual nanofibrous mats for enhanced nutrient delivery: A novel approach using chitosan-based nanoparticles
(ICEMES, 2025)There are many different types of dietary supplements that provide vital chemicals to the people they need to stay healthy. Oral administration offers convenience, yet it also presents notable drawbacks, including the ... -
Discovery of dual-inhibitor acyl hydrazones for acetylcholinesterase and carbonic anhydrase I/II: A mechanistic insight into Alzheimer's disease
(John Wiley and Sons Inc, 2025)This study presents the synthesis of various non-sulfonamide acyl hydrazone derivatives intended as multi-target ligands for the treatment of Alzheimer's disease. The derivatives were thoroughly characterized using advanced ... -
Donepezil/Curcumin-Loaded Nanoparticles-Embedded Microneedles for the treatment of Alzheimer’s disease: In vitro evaluation
(Avestia Publishing, 2024)Alzheimer’s disease (AD) is an insidious neurodegenerative disease that slowly deteriorates and seriously impairs the activity of daily living (ADL) of those who suffer from. Although the precise pathophysiology of AD ... -
Evaluation of the mesalazine-loaded nanoparticles-embedded BSA hydrogels for the ulcerative colitis treatment
(ACG Publications, 2024)Ulcerative colitis (UC) is a chronic inflammatory bowel disease mainly affecting the colon and remains a challenging disease to manage clinically with its relapsing-remitting course. Traditional treatments for this ... -
Fabrication of oro-dispersible sodium valproate loaded nanofibrous patches for immediate epileptic innervation
(American Chemical Society, 2024)Epilepsy is one of the oldest neurological disorders discovered by mankind. This condition is firmly coupled with unprovoked seizures stimulated by irrepressible neuroelectrical blasts. Orally taken valproate family has ... -
Gilaburu (Viburnum opulus L.) fruit extract has potential therapeutic and prophylactic role in a rat model of acetic acid-induced oxidant colonic damage
(Elsevier, 2024)Ethnopharmacological relevance: Ulcerative colitis (UC) which has a global impact on the health care system with its recurrent and incompletely curable characteristics, affects the patients’ quality of life. Gilaburu (GB; ... -
In vitro investigation of antimicrobial activities of Camellia sinensis, Salvia officinalis, Aloe vera and Thymus vulgaris
(Kızılay Culture and Art, 2025)Acne vulgaris is a skin condition that affects people of various age groups worldwide. It can lead to psychological disorders by negatively impacting individuals’ social lives, self-confidence, physical appearance, and ... -
In vitro neuroprotective effect evaluation of donepezil-loaded PLGA nanoparticles-embedded PVA/PEG nanofibers on SH-SY5Y cells and AP-APP plasmid related Alzheimer cell line model
(John Wiley and Sons Inc, 2024)Recently developed nanoparticles and nanofibers present new brain-specific treatment strategies, especially for Alzheimer's disease treatment. In this study, donepezil (DO)-loaded PLGA nanoparticles (DNP) are embedded in ... -
Investigation of the antimicrobial activity of some plant extracts
(Kızılay Culture and Art, 2025)The use of antimicrobial plants in mineral water prevents the growth of pathogenic microorganisms, extends the shelf life of the product, and pro vides a natural alternative to chemical preservatives (1). Furthermore, ... -
Liposomal coenzyme Q10/vitamin C: An innovative approach to enhance bioavailability andanti-inflammatory effects in neurological diseases via in vitro cell culture and in vivo animal tests
(Kızılay Culture and Art, 2025)Internal or external stressors may trigger a systemic hyperactive immune re sponse that results in widespread dysregulation and the potential for irrevers ible damage to vital organs. The potential of antioxidants such as ... -
The methanolic extracts of Teucrium polium L. and Micromeria fruticosa (L.) Druce subsp. brachycalyx P. H. Davis improve diabetes in streptozotocin/nicotinamide-induced type 2 diabetic female Sprague Dawley rats
(Elsevier, 2023)Background: Teucrium polium and Micromeria fruticosa subspecies are known to be used in tradi tional medicine for diabetes treatment. Objective: The present study aimed to examine the potential antidiabetic effects and ... -
A novel high-efficiency transdermal patches for combinational therapy of Alzheimer's disease: Donepezil/vitamin B12-loaded nanofibers
(Editions de Sante, 2023)Improving clinical practice in disease-modifying therapies is an important strategy in coping with the progressive course of Alzheimer’s Disease (AD). This study aimed to develop DO and VB12-loaded nanofibers (DO/VB12- ... -
Novel hydrazide-hydrazone containing 1,2,4-triazole as potent inhibitors of antiapoptotic protein Bcl-xL: Synthesis, biological evaluation, and docking studies
(John Wiley and Sons Inc, 2024)This study describes the synthesis and characterization of a series of novel hydrazide-hydrazone derivatives containing a 1,2,4-triazole ring. The compounds were characterized using various spectroscopic techniques, such ...
